| Cat.No.: | BSM-0247 |
| Product Name: | UNC0379 |
| CAS No.: | 1620401-82-2 |
| Figure: |
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| Synonyms: | 6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine |
| Description: | UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SET8 (IC₅₀ = 7.3 µM; Kd = 18.3 µM). It is selective for SET8 over 15 other methyltransferases, including G9a and GLP (IC₅₀s = >100 µM). |
| Appearance: | Crystalline solid |
| Molecular Weight: | 413.56 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | Lysine methyltransferase SET8 |
| Molecular Formula: | C₂₃H₃₅N₅O₂ |
| MDL Number: | MFCD00236452 |
| Solubility: | DMSO (~20 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0030 | SETD8 Polyclonal Antibody | Inquiry |
| EAb-0031 | SETDB1 Polyclonal Antibody | Inquiry |
| EAb-0032 | Setd1a Polyclonal Antibody | Inquiry |
| EAb-0033 | Setd1b Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| SENP3 | SENP8 | SET | SET1 |
| SET2 | SET7 | SET8 | SET9 |
| SETBP1 | SETD1A | SETD1B | SETD2 |
| SETD3 | SETD5 | SETD6 | SETD7 |
| SETD8 | SETD9 | SetDB1 | SETDB2 More > |
| SETMAR | |||
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