| Cat.No.: | BSM-0234 |
| Product Name: | Tenovin-1 |
| CAS No.: | 380315-80-0 |
| Figure: |
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| Synonyms: | N-[[[4-(Acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide |
| Description: | Tenovin-1 is a small molecule p53 activator that protects against MDM2-mediated p53 degradation. It acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Tenovin-1 protects against MDM2-mediated p53 degradation via ubiquitination. |
| Appearance: | White solid |
| Molecular Weight: | 369.48 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | Sirt1 and Sirt2 |
| Molecular Formula: | C20H23N3O2S |
| MDL Number: | MFCD02914760 |
| Solubility: | DMSO (~ 8 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
| EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
| EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
| SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
| Related Gene / Proteins | |||
| Siah2 | SIK1 | SIMC1 | SIN3A |
| SIN3B | SIP1 | Sir2p | SIRT |
| SIRT1 | SIRT2 | SIRT3 | SIRT4 |
| SIRT5 | sirt6 | SIRT7 | SIX3 |
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