| Cat.No.: | BSM-0206 |
| Product Name: | Ruxolitinib, Free base |
| CAS No.: | 941678-49-5 |
| Figure: |
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| Synonyms: | INCB018424; INC18424; NCB018424; NCB18424 |
| Description: | Ruxolitinib is a potent and selective Janus kinase (JAK) inhibitor with IC₅₀'s of 2.7 and 4.5 nM for JAK1 and JAK2, respectively. Displays clinically significant activity in myelofibrosis. |
| Appearance: | Off-white solid |
| Molecular Weight: | 306.37 |
| Purity: | ≥99% by HPLC |
| Storage: | -20°C |
| Targets: | JAK |
| Molecular Formula: | C₁₇H₁₈N₆ |
| MDL Number: | MFCD12031592 |
| Solubility: | DMSO (25 mg/ml) or EtOH (~ 15 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0002 | AT9283 | Inquiry |
| ◆ Cell Lines | ||
| CL-0017 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| CL-0081 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0079 | JARID2 Polyclonal Antibody | Inquiry |
| EAb-0080 | JARID1C Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JADE1 | JAK | JAK1 | JAK2 |
| JAK3 | JAKMIP1 | JARID | JARID1 |
| JARID1A | JARID1B | JARID1C | JARID2 |
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