| Cat.No.: | BSM-0197 |
| Product Name: | PX 12 |
| CAS No.: | 141400-58-0 |
| Figure: |
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| Synonyms: | 2-[(1-Methylpropyl)dithio]-1H-imidazole; IV-2 |
| Description: | PX-12 is an irreversible inhibitor of thioredoxin-1 (TRX-1) (Ki = 31 µM). It decreases the expression of HIF-1α, VEGF and iNOS (IC₅₀ values are 7.2, ~10 and 18.1 μM respectively). Also known to display antitumor activity and inhibits tubulin polymerization in vitro. |
| Appearance: | Beige solid |
| Molecular Weight: | 188.31 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | Thioredoxin-1 (TRX-1) |
| Molecular Formula: | C₇H₁₂N₂S₂ |
| MDL Number: | MFCD18086851 |
| Solubility: | DMSO (100 mM) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| BSM-0021 | PF-03814735 | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0107 | Recombinant Human TRIM68 293 Cell Lysate | Inquiry |
| EL-0109 | Recombinant Human TRIP4 Lysate | Inquiry |
| EL-0115 | Recombinant Human TRIM24 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| TRA2A | TRAF4 | TRAF5 | TRAF6 |
| TRAK2 | TRBP | TRDMT1 | TREX1 |
| TRF2 | TRIM11 | TRIM13 | TRIM16 |
| TRIM17 | TRIM2 | TRIM21 | trim24 |
| TRIM26 | TRIM28 | TRIM3 | TRIM33 More > |
| TRIM34 | TRIM35 | TRIM36 | TRIM37 |
| TRIM38 | TRIM39 | TRIM4 | TRIM5 |
| TRIM55 | TRIM6 | TRIM63 | TRIM66 |
| TRIM68 | TRIM8 | TRIM9 | TRIML1 |
| TRIP4 | Tristetraprolin | TRIT1 | TrkA |
| TRMT2A | TRMT44 | TRMT5 | TRMT6 |
| TROVE2 | TRUB2 | TRX1 | TRβ1 |
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