| Cat.No.: | BSM-0196 |
| Product Name: | Plumbagin |
| CAS No.: | 481-42-5 |
| Figure: |
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| Synonyms: | 5-Hydroxy-2-methyl-1,4-naphthalenedione |
| Description: | A quinonoid constituent isolated from the root of Plumbago zeylanica. Displays anticarcinogenic, antiatherosclerotic, and antimicrobial effects as well as anticancer and antiproliferation properties in a variety of cell lines and animal models. Induces G2/M and autophagy in breast cancer cells by inhibiting Akt/mTOR pathway. Also potently inhibits histone acetyltransferase (HAT) activity in vivo. Plumbagin specifically inhibits p300-mediated acetylation of p53 but not the acetylation by p300/CREB-binding protein associated factor, PCAF, in vivo. |
| Appearance: | Orange red solid |
| Molecular Weight: | 188.18 |
| Purity: | ≥98% |
| Storage: | -20 ̊C |
| Targets: | Histone acetyltransferase |
| Molecular Formula: | C₁₁H₈O₃ |
| MDL Number: | MFCD00001682 |
| Solubility: | DMSO (~20 mg/ml) or EtOH (~10 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0038 | CTPB | Inquiry |
| BSM-0073 | Anacardic Acid | Inquiry |
| BSM-0094 | C646 | Inquiry |
| BSM-0108 | Curcumin, Curcuma longa (High Purity) | Inquiry |
| ◆ Cell Lines | ||
| CL-0061 | Human EP300 Knockout Cell Line 13bp deletion | Inquiry |
| Related Gene / Proteins | |||
| EP300 | EPC1 | ||
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