| Cat.No.: | BSM-0177 |
| CAS No.: | 5262-39-5 |
| Figure: |
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| Synonyms: | 2-(Carboxymethylamino)-2-oxoacetic acid |
| Description: | N-Oxalylglycine, the amide analog of α-ketoglutarate, is a cell-permeable inhibitor of α-ketoglutarate-dependent enzymes, including JMJD2A, JMJD2C, and JMJD2E (IC₅₀s = 250, 500, and 24 μM, respectively). It can also inhibit the prolyl hydroxylase domain-containing proteins PHD1 and PHD2 with IC₅₀ values of 2.1 and 5.6 μM, respectively. |
| Appearance: | White Solid |
| Molecular Weight: | 147.1 |
| Purity: | ≥95% by HPLC |
| Storage: | -20°C |
| Targets: | α-ketoglutarate-dependent enzymes |
| Molecular Formula: | C₄H₅NO₅ |
| MDL Number: | MFCD00913253 |
| Solubility: | DMSO (~10 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0072 | JMJD6 Polyclonal Antibody | Inquiry |
| EAb-0074 | JMJD2c Polyclonal Antibody | Inquiry |
| EAb-0075 | JMJD2b Polyclonal Antibody | Inquiry |
| EAb-0076 | JMJD2A Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JMJD | JMJD1A | JMJD1B | JMJD1C |
| JMJD2 | JMJD2A | JMJD2B | JMJD2C |
| JMJD2D | JMJD2E | JMJD2F | JMJD3 |
| JMJD4 | JMJD5 | JMJD6 | |
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