| Cat.No.: | BSM-0170 |
| Product Name: | MI-3 |
| CAS No.: | 1271738-59-0 |
| Figure: |
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| Synonyms: | 4-(4-(5,5-dimethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-isopropylthieno[2,3-d]pyrimidine; Menin-MLL inhibitor 3 |
| Description: | MI-3 is a Menin-MLL (Mixed linage leukemia) protein interaction inhibitor with an IC₅₀ of 648 ± 25 nM. MLL protein is a histone methyltransferase that positively regulates gene transcription. However, MLL gene is a common target for chromosomal translocations found in some leukemia. |
| Appearance: | Crystalline solid |
| Molecular Weight: | 375.55 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | Menin-MLL (Mixed linage leukemia) protein interaction |
| Molecular Formula: | C₁₈H₂₅N₅S₂ |
| MDL Number: | MFCD03453554 |
| Solubility: | DMSO (~5 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0170 | MI-3 | Inquiry |
| BSM-0187 | OICR-9429 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0172 | Human KMT2C / MLL3 peptide | Inquiry |
| ◆ Research Kits | ||
| EKIT-0285 | MLL1 Complex Chemiluminescent Assay Kit | Inquiry |
| EKIT-0286 | MLL1 SAM-Screener Assay Kit | Inquiry |
| Related Gene / Proteins | |||
| MLH1 | MLL | mll1 | MLL2 |
| MLL3 | MLL4 | MLL5 | MLLT1 |
| MLLT3 | |||
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