| Cat.No.: | BSM-0155 |
| Product Name: | ITSA-1 |
| CAS No.: | 200626-61-5 |
| Figure: |
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| Synonyms: | N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide, ITSA1 |
| Description: | Cell-permeable. ITSA-1 is a suppressor of Trichostatin A (TSA) and a molecular tool for dissecting gene regulation by distinct acetylation events (histone and tubulin). ITSA-1 specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors. ITSA-1 reverses TSA induced histone acetylation, overall deacetylation. ITSA-1 also reverses TSA induced cell cycle arrest and apoptosis. |
| Appearance: | White solid |
| Molecular Weight: | 292.12 |
| Purity: | ≥98% by TLC |
| Storage: | -20°C |
| Targets: | Histone deacetylase (HDAC) |
| Molecular Formula: | C₁₃H₇Cl₂N₃O |
| MDL Number: | MFCD00195103 |
| Solubility: | DMSO (25 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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