| Cat.No.: | BSM-0147 |
| Product Name: | Hyperforin. DCHA |
| CAS No.: | 238074-03-8 |
| Figure: |
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| Synonyms: | 5-hydroxy-6R-methyl-1R,3,7S-tris(3-methyl-2-butenyl)-5S-(2- methyl-1-oxopropyl)-6R-(4-methyl-3-pentenyl)-bicyclo[3.3.1]non- 3-ene-2,9-dione. DHCA |
| Description: | Displays a variety of biological activities including anti-bacterial, anti-inflammatory, anticancer and anti-angiogenic effects. Also acts as an antidepressant and anxiolytic agent. Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Also acts as a potent SIRT1 and SIRT2 inhibitor. |
| Appearance: | White to off-white solid |
| Molecular Weight: | 718.1 |
| Purity: | ≥97% by HPLC |
| Storage: | -20°C |
| Targets: | SIRT1 and SIRT2 |
| Molecular Formula: | C₃₅H₅₂O₄.C₁₂H₂₃N |
| MDL Number: | MFCD04000098 |
| Solubility: | DMSO or EtOH |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
| EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
| EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
| SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
| Related Gene / Proteins | |||
| Siah2 | SIK1 | SIMC1 | SIN3A |
| SIN3B | SIP1 | Sir2p | SIRT |
| SIRT1 | SIRT2 | SIRT3 | SIRT4 |
| SIRT5 | sirt6 | SIRT7 | SIX3 |
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