| Cat.No.: | BSM-0118 |
| CAS No.: | 2098546-05-3 |
| Figure: |
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| Synonyms: | EBI2511, N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-ethyl-6-(ethyl-(tetrahydro-2H-pyran-4-yl)amino)-2-(1-isopropylpiperidin-4-yl)benzofuran-4-carboxamide |
| Description: | EBI-2511 is a highly potent and orally active EZH2 inhibitor with an IC₅₀ of 4 nM for EZH2(A667G). EBI-2511 displays excellent in vivo efficacy in Pfeiffer tumor Xenograft models in mouse and could be useful for the treatment of cancers associated with EZH2 mutations. |
| Appearance: | Crystalline solid |
| Molecular Weight: | 576.77 |
| Purity: | ≥98% by HPPC |
| Storage: | -20ºC |
| Targets: | EZH2 |
| Molecular Formula: | C₃₄H₄₈N₄O₄ |
| MDL Number: | MFCD00830384 |
| Solubility: | >25 mg/ml in DMSO |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0006 | GSK343 | Inquiry |
| BSM-0059 | 3-Deazaneplanocin A | Inquiry |
| BSM-0060 | 3-Deazaneplanocin A hydrochloride | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0024 | Recombinant Human EZH1 293 Cell Lysate | Inquiry |
| EL-0025 | Recombinant Human EZH2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| ezh1 | EZH2 | ||
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