| Cat.No.: | BSM-0100 |
| Product Name: | Chaetocin |
| CAS No.: | 28097-03-2 |
| Figure: |
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| Synonyms: | (3S,3'S,5aR,5aR,10bR,10'bR,11aS,11'aS)-2,2',3,3',5a,5'a,6,6'-octahydro-3,3'-bis(hydroxymethyl)-2,2'-dimethyl-[10b,10'b(11H,11'H)-bi3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone |
| Product Overview: | A selective histone lysine methyltransferase (HKMT) inhibitor |
| Description: | Inhibits the lysine methyltransferase SU(VAR)3-9. Displays anti-myeloma activity in IL-6 dependent myeloma cell lines.It also has some inhibitory effects on SET7, EZH2, and SET7/9. Chaetocin can also induce cellular oxidative stress, selectively killing cancer cells and rapidly-proliferating primary cells. It is a fungal myotoxin. Cell permeable. |
| Appearance: | Off-white solid |
| Molecular Weight: | 696.84 |
| Purity: | ≥95% |
| Storage: | -20°C |
| Targets: | SU(VAR)3-9 |
| Molecular Formula: | C30H28N6O6S4 |
| MDL Number: | MFCD00133163 |
| Solubility: | Dissolved in DMSO (25 mg/ml); Ethanol (25 mg/ml). |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0020 | Suz12 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0100 | Chaetocin | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0103 | Recombinant Human SUZ12 293 Cell Lysate | Inquiry |
| EL-0132 | Recombinant Human SUV39H1 293 Cell Lysate | Inquiry |
| EL-0137 | Recombinant Human SUV420H1 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| SUDS3 | SUMO | SUMO1 | SUMO2 |
| SUMO3 | SUN1 | Surf6 | suv39h1 |
| SUV39H2 | SUV3L1 | SUV420H1 | SUV420H2 |
| SUZ12 | |||
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