| Cat.No.: | BSM-0085 |
| Product Name: | BG-45 |
| CAS No.: | 926259-99-6 |
| Figure: |
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| Synonyms: | N-(2-Aminophenyl)pyrazine-2-carboxamide |
| Description: | BG-45 is a potent HDAC class I inhibitor with selectivity for HDAC3 (IC₅₀ = 289 nM) over HDAC1, 2. BG45 does not inhibit HDAC6. BG-45 alone or in combination with bortezomib has been shown to dose-dependently inhibit tumor growth in a mouse model of multiple myeloma. |
| Appearance: | White to of-white solid |
| Molecular Weight: | 214.23 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | HDAC class I |
| Molecular Formula: | C₁₁H₁₀N₄O |
| MDL Number: | MFCD16038904 |
| Solubility: | DMSO (>20 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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