| Cat.No.: | BSM-0080 |
| Product Name: | AZ-505 ditrifluoroacetate |
| CAS No.: | 1035227-44-1 |
| Figure: |
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| Synonyms: | N-cyclohexyl-3-[2-(3,4-dichlorophenyl)ethylamino]-N-[2-[2-(5-hydroxy-3-oxo-4H-1,4-benzoxazin-8-yl)ethylamino]ethyl]propenamide bis(2,2,2-trifluoroacetate) |
| Description: | AZ-505 is a potent and highly selective inhibitor of SMYD2 (IC₅₀ = 0.12 μM) with potential anticancer activity. Displays >600-fold selectivity over other histone methyltransferases, such as SMYD3 (IC₅₀>83.3 μM), DOT1L (IC₅₀>83.3 μM) and EZH2 (IC₅₀>83.3 μM). |
| Appearance: | Crystalline solid |
| Molecular Weight: | 805.59 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | SMYD2 |
| Molecular Formula: | C₃₃H₄₀Cl₂F₆N₄O₈ |
| MDL Number: | MFCD10687152 |
| Solubility: | DMSO |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0019 | SMARCA4 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0063 | Recombinant Human SMARCC2 293 Cell Lysate | Inquiry |
| EL-0064 | Recombinant Human SMARCB1 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0080 | AZ-505 ditrifluoroacetate | Inquiry |
| ◆ Research Kits | ||
| EKIT-0120 | BRG1 bromodomain TR-FRET Assay Kit | Inquiry |
| Related Gene / Proteins | |||
| SMAD3 | SMAD4 | SMARCA1 | SMARCA2 |
| SMARCA4 | SMARCA5 | SMARCA6 | SMARCAD1 |
| SMARCAL1 | SMARCB1 | SMARCC1 | SMARCC2 |
| SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 |
| SMC1-α | SMC3 | SMC4 | SMCHD1 More > |
| SMCX | SMN | SMN1 | SMN2 |
| SMOC2 | SMRT | SMT3 | SMUG1 |
| SMURF2 | SMYD1 | SMYD2 | SMYD2B |
| SMYD3 | SMYD4 | SMYD5 | |
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