| Cat.No.: | BSM-0078 |
| Product Name: | ATM Kinase Inhibitor, KU-55933 |
| CAS No.: | 587871-26-9 |
| Figure: |
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| Synonyms: | 2-Morpholin-4-yl-6-thianthren-1-yl-pyran-4-one; KU-55933 |
| Description: | A potent, selective and ATP-competitive inhibitor of ATM Kinase (Ki = 2.2 nM; IC₅₀ = 13 nM). Inhibits DNA-PK, mTOR, PI 3-K, PI 4-K, and ATR at much higher concentrations (IC₅₀ = 2500, 9300, 16600, >100000 and >100000 nM, respectively). |
| Appearance: | White solid |
| Molecular Weight: | 395.49 |
| Purity: | ≥97% by HPLC |
| Storage: | -20°C |
| Targets: | ATM kinase |
| Molecular Formula: | C₂₁H₁₇NO₃S₂ |
| MDL Number: | MFCD08276985 |
| Solubility: | DMSO (100 mM) and Ethanol (50 mM) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0020 | Human ATAD2 Knockout Cell Line 2bp deletion | Inquiry |
| CL-0021 | Human ATAD2B Knockout Cell Line 130bp insertion | Inquiry |
| CL-0022 | Human ATAD2B Knockout Cell Line 130bp insertion | Inquiry |
| ◆ Research Kits | ||
| EKIT-0021 | ATF2 (pT69/pT71) Transcription Factor Assay Kit | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0031 | Recombinant Human ATAD2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| ATAD2 | ATAT1 | ATF-6 | ATF1 |
| ATF2 | ATF4 | ATM | ATR |
| ATRX | ATXN3 | ATXN3L | ATXN7 |
| ATXN7L3 | |||
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