| Cat.No.: | BSM-0075 |
| Product Name: | AR-42 (OSU-HDAC42) |
| CAS No.: | 935881-37-1 |
| Figure: |
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| Synonyms: | S)-N-hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide |
| Description: | AR-42 is a potent histone deacetylase inhibitor (HDACi). It induces growth inhibition, cell- cycle arrest, apoptosis, and activation of caspases-3/7. AR-42 treatment induces histone hyperacetylation and p21WAF/CIP1 overexpression, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells. |
| Appearance: | Crystalline solid |
| Molecular Weight: | 312.36 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | HDAC |
| Molecular Formula: | C18H20N2O3 |
| MDL Number: | MFCD17676151 |
| Solubility: | DMSO (~ 20 mg/ml) or EtOH (~ 20 mg/ml |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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