| Cat.No.: | BSM-0048 |
| Product Name: | Sinefungin |
| CAS No.: | 58944-73-3 |
| Figure: |
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| Synonyms: | Sinefungin, 5'-Deoxy-5'-(1,4-diamino-4-carboxybutyl)adenosine; A-9145; Adenosylornithine; Antibiotic 32232RP |
| Description: | Nucleoside S-adenosyl-1-methionine analog. Potent, competitive methyltransferase (protein, DNA, and RNA methyltransferase) inhibitor. IC50 > 1.0 and 2.5 µM for PRMT1 and SET7/9, respectively. Binds with greater affinity to the adenine-specific DNA methyltransferase M.TaqI than S-adenosyl-L-homocysteine. Inhibits biofilm formation by Streptococcus pneumoniae. |
| Appearance: | Tan powder. |
| Molecular Weight: | 381.4 |
| Purity: | >98% (HPLC); NMR (Conforms) |
| Storage: | Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month. |
| Molecular Formula: | C15H23N7O5 |
| Solubility: | Dissolved in water (20 mg/ml). |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
| EL-0029 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| EL-0030 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| DNA alkyltransferase | DNAJC2 | DNAS1L1 | DNASE1L3 |
| DNMT | DNMT1 | DNMT2 | DNMT3A |
| DNMT3B | DNMT3L | DNMT4 | |
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