Chromatin DNA-Protein Interation Analyzer


Cat.No: CTLP-LJX-0001 Product Datasheets

Product Name: Chromatin DNA-Protein Interation Analyzer

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Description:  CUT&Tag (Cleavage Under Targets and Tagmentation) is a contemporary and sensitive technique for profiling chromatin-associated proteins and histone modifications, offering superior signal-to-noise ratio and lower input requirements compared to traditional ChIP-seq. To maximize its potential and accessibility, we have developed the Chromatin DNA-Protein Interaction Analyzer. This fully automated system transforms the multi-step, manual CUT&Tag protocol into a streamlined, push-button workflow. Simply load your prepared cell or nuclei suspension, and the instrument automatically executes the entire process—from cell capture and antibody incubation to tagmentation and library amplification—culminating in the generation of high-quality, sequencing-ready CUT&Tag libraries. It ensures exceptional reproducibility, minimizes hands-on time, and enables researchers to consistently obtain robust epigenetic data from precious biological samples.
Workflow:  • Cell Capture • Antibody Incubation • Transposase Incubation • DNA Fragment Recovery • PCR Reaction Solution Preparation • Library Purification
Sample Types:  Animal cells, animal cell nuclei, plant cell nuclei, cell nuclei cross-linked with 0.01%-0.3% formaldehyde
Sample Throughput:  1-16 samples can be processed simultaneously
Antibodies:  Supports 1-4 primary antibodies and 1-2 secondary antibodies
Cell Sample Quantity:  Each sample contains 500-50,000 cells (nuclei)
Library Construction Time:  Library construction of 1-16 samples can be completed within 7.5 hours
Reagents:  Pre-fabricated reagent cartridges, requiring almost no manual operation
Temperature Control Module:  The reagent storage area supports cooling to 4°C, and the reaction area supports heating from room temperature to 60°C. The heating module adopts a bottom-fully enclosed and side-partially enclosed heating method, which ensures rapid heating and strong temperature stability.
Magnetic Module:  Permanent magnet column, 4000Gs~6000Gs; magnetic bead recovery rate, >98%
User Interface:  10.1-inch full-color LCD touchscreen
Illumination:  Built-in LED lights, freely switchable via the screen
Contamination Control:  Built-in UV disinfection module
Note:  The instrument has functions such as self-test upon startup, silent operation, power failure protection, and over-temperature protection, which can minimize sample loss during instrument use.

Supporting Reagents

Cat No Product Name Specifications
CTLP-LJX-0002 Chromatin DNA-Protein Interaction Kit 4T
CTLP-LJX-0003 Chromatin DNA-Protein Interaction Kit 16T

The kit includes all necessary reagents such as cell capture beads, various buffers, Tn5 transposase, library purification beads, PCR Mix, and index primers.

* Primary and secondary antibodies need to be provided by the user.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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