| Cat.No.: | PE-3461 |
| Product Name: | Recombinant METTL1 protein |
| Product Overview: | Recombinant METTL1 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_005362.3) with an N-terminal FLAG tag. The molecular weights of METTL1 is 32.7 kDa. |
| Background: | METTL1 (methyltransferase-like 1, also known as TRM8, TRMT8, C12orf1, YDL201w) contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. METTL1 forms a stable heterodimer complex with WDR4, which catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. |
| Applications: | Suitable for use in binding assays, inhibitor screening, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | 25 mM HEPES pH 7.5, 300 mM NaCl, 5% glycerol, 0.04% Triton X-100, 0.2 mM TCEP. |
| Tag: | FLAG |
| Expression System: | Baculovirus |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0043 | Recombinant Human MECP2 293 Cell Lysate | Inquiry |
| EL-0111 | Recombinant Human MEF2B Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0067 | MeCP2 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0109 | Human MECP2 Knockout Cell Line 1bp insertion | Inquiry |
| CL-0110 | Human MEN1 Knockout Cell Line 1bp insertion | Inquiry |
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