| Cat.No.: | PE-3427 |
| Product Name: | Recombinant MLLT1 / ENL (1-148) protein |
| Product Overview: | Recombinant human MLLT1 / ENL (1-148) that includes amino acids 1-148 (accession number NP_005925.2) was expressed in E. coli cells with an N-terminal 6×His tag and a C-terminal Flag tag. The molecular weight of the protein is 21.9 kDa. |
| Background: | MLLT1 / ENL (Myeloid/Lymphoid Or Mixed-Lineage Leukemia; Translocated To, 1), also known as YEATS1 or LTG19, is a component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. |
| Applications: | Suitable for use in enzyme kinetics, inhibitor screening, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | 25 mM Tris- HCl pH 8.0, 300 mM NaCl, 10% glycerol and 0.5 mM TCEP. |
| Tag: | His & FLAG |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0170 | MI-3 | Inquiry |
| BSM-0187 | OICR-9429 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0172 | Human KMT2C / MLL3 peptide | Inquiry |
| ◆ Research Kits | ||
| EKIT-0285 | MLL1 Complex Chemiluminescent Assay Kit | Inquiry |
| EKIT-0286 | MLL1 SAM-Screener Assay Kit | Inquiry |
| Related Gene / Proteins | |||
| ENDOD1 | ENDOGL1 | ENGL | ENL |
| ENY2 | MLH1 | MLL | mll1 |
| MLL2 | MLL3 | MLL4 | MLL5 |
| MLLT1 | MLLT3 | ||
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