| Cat.No.: | PE-3271 |
| Description: | Recombinant human BRD3 Bromodomain 1 (RING3L, accession number Q15059, amino acids 25 to 160) containing an N-terminal GST tag, expressed in E. coli. BRD3 is a member of the BET sub-family of bromodomain-containing proteins, which also includes BRD2, BRD4 and BRDT. BET proteins have two bromodomains and an ET domain C-terminal to the second bromodomain. BRD3 interacts with acetylated histone and non-histone proteins, including acetylated GATA1. BRD3 is found fused to the NUT protein in a subset of carcinomas, contributing to the oncogenic phenotype by suppressing differentiation. |
| Applications: | Recombinant BRD3 Bromodomain 1 is useful for protein binding and screening experiments examining acetylated protein substrates. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 41 kDa |
| Species: | Human |
| Formulation: | in 20 mM Tris-HCl pH 8.0, 200 mM NaCl, 1 mM DTT, 20% glycerol. |
| Tag: | GST |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0001 | Bromodomain Non-Acetylated Ligand 4 | Inquiry |
| SP-0002 | Bromodomain Non-Acetylated Ligand 3 | Inquiry |
| SP-0003 | Bromodomain Non-Acetylated Ligand 1 | Inquiry |
| SP-0004 | Bromodomain Ligand 3 | Inquiry |
| SP-0006 | Bromodomain Ligand 4 | Inquiry |
| Related Gene / Proteins | |||
| BRCA1 | BRCA2 | BRCC3 | BRD |
| brd1 | brd2 | brd3 | brd4 |
| BRD7 | BRD8 | brd9 | brdt |
| BRL | BRM | BRMS1 | BRPF1 |
| BRPF2 | brpf3 | BRWD1 | BRWD3 |
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