| Cat.No.: | PE-3263 |
| Product Name: | SMYD3, Recombinant Human |
| Description: | Recombinant full-length human SMYD3 protein, (SET and MYND domain-containing protein 3, ZMYND1, ZNFN3A1, accession Q9H7B4), containing an N-terminal GST tag, expressed in E. coli. SMYD3 is a protein lysine methyltransferase that has been shown to catalyze mono-, di-, and tri-methylation of histone H4 at lysine 5 by multiple independent approaches, including mass spectrometry. SMYD3 levels are up-regulated in a large number of tumors, including liver, breast and rectal carcinomas. SMYD3 overexpression promotes the proliferation of cancer cells, while its depletion slows expansion. |
| Applications: | Recombinant SMYD3, human is useful for histone H4 methylation experiments, enzyme kinetics and inhibitor screening. Use of 1-3 µg SMYD3 per reaction with recombinant histone H4 as a substrate is recommended. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 68 kDa |
| Species: | Human |
| Formulation: | in 100mM Tris pH 8.0, 10 mM glutathione and 10% glycerol. |
| Tag: | GST |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0019 | SMARCA4 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0063 | Recombinant Human SMARCC2 293 Cell Lysate | Inquiry |
| EL-0064 | Recombinant Human SMARCB1 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0080 | AZ-505 ditrifluoroacetate | Inquiry |
| ◆ Research Kits | ||
| EKIT-0120 | BRG1 bromodomain TR-FRET Assay Kit | Inquiry |
| Related Gene / Proteins | |||
| SMAD3 | SMAD4 | SMARCA1 | SMARCA2 |
| SMARCA4 | SMARCA5 | SMARCA6 | SMARCAD1 |
| SMARCAL1 | SMARCB1 | SMARCC1 | SMARCC2 |
| SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 |
| SMC1-α | SMC3 | SMC4 | SMCHD1 More > |
| SMCX | SMN | SMN1 | SMN2 |
| SMOC2 | SMRT | SMT3 | SMUG1 |
| SMURF2 | SMYD1 | SMYD2 | SMYD2B |
| SMYD3 | SMYD4 | SMYD5 | |
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