| Cat.No.: | PE-3056 |
| Description: | SMYD2 has been described as a histone H3 (H3K4, H3K36), p53 (p53K370) and Rb (retinoblastoma; RbK860) lysine methyltransferase, although RBC finds this recombinant SMYD2 preparation to be far more active in vitro with recombinant histone H4 than with histone H3, an H3(1-21) peptide, an H4(1-21) peptide, core histones or recombinant p53. SMYD2 is frequently overexpressed in esophageal squamous cell carcinoma (ESCC) and SMYD2 knockdown inhibits the proliferation of SMYD2-overexpressing ESCC cell lines. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 52.0 kDa |
| Formulation: | Solution of purified recombinant protein in 20 mM Tris/HCl, pH 8.0, 120 mM NaCl, 1 mM TCEP, 1 µM ZnCl2, 10% (w/v) glycerol |
| Accession#: | NM_020197 |
| Tag: | His |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0019 | SMARCA4 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0063 | Recombinant Human SMARCC2 293 Cell Lysate | Inquiry |
| EL-0064 | Recombinant Human SMARCB1 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0080 | AZ-505 ditrifluoroacetate | Inquiry |
| ◆ Research Kits | ||
| EKIT-0120 | BRG1 bromodomain TR-FRET Assay Kit | Inquiry |
| Related Gene / Proteins | |||
| SMAD3 | SMAD4 | SMARCA1 | SMARCA2 |
| SMARCA4 | SMARCA5 | SMARCA6 | SMARCAD1 |
| SMARCAL1 | SMARCB1 | SMARCC1 | SMARCC2 |
| SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 |
| SMC1-α | SMC3 | SMC4 | SMCHD1 More > |
| SMCX | SMN | SMN1 | SMN2 |
| SMOC2 | SMRT | SMT3 | SMUG1 |
| SMURF2 | SMYD1 | SMYD2 | SMYD2B |
| SMYD3 | SMYD4 | SMYD5 | |
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