| Cat.No.: | PE-2659 |
| Background: | Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. |
| Applications: | SDS-PAGE |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 37 kDa including tags |
| Purity: | >60 % SDS-PAGE. |
| Formulation: | pH: 8.00; Preservative: 1.36% Imidazole; Constituents: 0.02% Potassium chloride, 0.63% Tris HCl, 20% Glycerol, 0.64% Sodium chloride |
| Accession#: | A4YCD7 |
| Alternative Names: | ada/ADA_HUMAN/ADA1 |
| Tag: | His |
| Amino Acid Sequence: | IDTSIPLVDLHRHLDGNVRVNTIWELGHQHGIALPADSLETLAPFVQIQG KETSLVAFLKKLDWMVAVLADLDAVKRVAYENVADAALSGLDYAELRFSP YYMAMNHKLPIEGVVEAVVDGVKAGLKDYNVKINLIGIMSRSFGQAACTQ ELEGLLAHKQHLVAMDLAGDELGFPGELFNDHFKRVRDAGLAITAHAGEA AGSQSMWQAIQELGATRIGHGVNAIHDPKLMEYLAKHRIGIESCPTSNLH TSTVVSYAEHPFRTFMDAGVLISLNTDDPGVSAIDIKHEYRIAKSELKLT DAELARVQRNGVEMAFLSDSERKALYAAKI |
| Sequence Similarities: | Belongs to the adenosine and AMP deaminases family. |
| Expression System: | E. coli |
| Protein Length: | Full length protein; 2 to 331 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0203 | ADNP Polyclonal Antibody | Inquiry |
| EAb-0370 | ADPRHL2 Polyclonal Antibody | Inquiry |
| ◆ Research Kits | ||
| EKIT-0580 | ADMA direct (mouse/rat) ELISA kit | Inquiry |
| EKIT-0581 | ADMA (human) ELISA kit | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2174 | Recombinant Human ADAL protein (denatured) | Inquiry |
| Related Gene / Proteins | |||
| ADA | ADAL | ADAR1 | ADMA |
| ADNP | ADPRH | ADPRHL2 | |
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