Recombinant human ADA protein

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Cat.No.:  PE-2430
Background:  Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.
Applications:  Functional Studies; SDS-PAGE; Mass Spectrometry
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Molecular Weight:  43 kDa
Purity:  > 85 % SDS-PAGE. No detergents such as urea, Triton or Tween were used to purify the proteins. Purified by using anion exchange chromatography (DEAE sepharose resin) and gel filtration chromatography (Sephacryl S 200) with 20mM Tris pH 7.5, 2mM EDTA.
Species:  Human
Formulation:  pH: 8.00; Constituents: 0.32% Tris HCl, 20% Glycerol, 0.02% DTT
Accession#:  P00813
Alternative Names:  ada/ADA_HUMAN/ADA1
Tag:  His
Amino Acid Sequence:  MGSSHHHHHH SSGLVPRGSH MAQTPAFDKP KVELHVHLDG SIKPETILYY GRRRGIALPA NTAEGLLNVI GMDKPLTLPD FLAKFDYYMP AIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVEPIPWNQA EGDLTPDEVV ALVGQGLQEG ERDFGVKARS ILCCMRHQPN WSPKVVELCK KYQQQTVVAI DLAGDETIPG SSLLPGHVQA YQEAVKSGIH RTVHAGEVGS AEVVKEAVDI LKTERLGHGY HTLEDQALYN RLRQENMHFE ICPWSSYLTG AWKPDTEHAV IRLKNDQANY SLNTDDPLIF KSTLDTDYQM TKRDMGFTEE EFKRLNINAA KSSFLPEDEK RELLDLLYKA YGMPPSASAG QNL
Sequence Similarities:  Belongs to the adenosine and AMP deaminases family.
Expression System:  E. coli
Protein Length:  Full length protein; 1 to 363
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Product Types
◆ Antibodies
EAb-0203 ADNP Polyclonal Antibody Inquiry
EAb-0370 ADPRHL2 Polyclonal Antibody Inquiry
◆ Research Kits
EKIT-0580 ADMA direct (mouse/rat) ELISA kit Inquiry
EKIT-0581 ADMA (human) ELISA kit Inquiry
◆ Proteins & Enzymes
PE-2174 Recombinant Human ADAL protein (denatured) Inquiry
Related Gene / Proteins
ADA ADAL ADAR1 ADMA
ADNP ADPRH ADPRHL2

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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