| Cat.No.: | PE-2430 |
| Background: | Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. |
| Applications: | Functional Studies; SDS-PAGE; Mass Spectrometry |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 43 kDa |
| Purity: | > 85 % SDS-PAGE. No detergents such as urea, Triton or Tween were used to purify the proteins. Purified by using anion exchange chromatography (DEAE sepharose resin) and gel filtration chromatography (Sephacryl S 200) with 20mM Tris pH 7.5, 2mM EDTA. |
| Species: | Human |
| Formulation: | pH: 8.00; Constituents: 0.32% Tris HCl, 20% Glycerol, 0.02% DTT |
| Accession#: | P00813 |
| Alternative Names: | ada/ADA_HUMAN/ADA1 |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAQTPAFDKP KVELHVHLDG SIKPETILYY GRRRGIALPA NTAEGLLNVI GMDKPLTLPD FLAKFDYYMP AIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVEPIPWNQA EGDLTPDEVV ALVGQGLQEG ERDFGVKARS ILCCMRHQPN WSPKVVELCK KYQQQTVVAI DLAGDETIPG SSLLPGHVQA YQEAVKSGIH RTVHAGEVGS AEVVKEAVDI LKTERLGHGY HTLEDQALYN RLRQENMHFE ICPWSSYLTG AWKPDTEHAV IRLKNDQANY SLNTDDPLIF KSTLDTDYQM TKRDMGFTEE EFKRLNINAA KSSFLPEDEK RELLDLLYKA YGMPPSASAG QNL |
| Sequence Similarities: | Belongs to the adenosine and AMP deaminases family. |
| Expression System: | E. coli |
| Protein Length: | Full length protein; 1 to 363 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0203 | ADNP Polyclonal Antibody | Inquiry |
| EAb-0370 | ADPRHL2 Polyclonal Antibody | Inquiry |
| ◆ Research Kits | ||
| EKIT-0580 | ADMA direct (mouse/rat) ELISA kit | Inquiry |
| EKIT-0581 | ADMA (human) ELISA kit | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2174 | Recombinant Human ADAL protein (denatured) | Inquiry |
| Related Gene / Proteins | |||
| ADA | ADAL | ADAR1 | ADMA |
| ADNP | ADPRH | ADPRHL2 | |
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