Recombinant Human JMJD5 protein

Cat.No.:	PE-2410
Product Name:	Recombinant Human JMJD5 protein
Background:	Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
Applications:	SDS-PAGE; Western blot; ELISA
Storage:	Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:	Liquid
Molecular Weight:	72 kDa including tags
Species:	Human
Formulation:	pH: 8.00; Constituents: 0.31% Glutathione, 0.79% Tris HCl
Accession#:	Q8N371
Alternative Names:	FLJ13798/JmjC domain-containing protein 5/JMJD5
Tag:	GST
Amino Acid Sequence:	MAGDTHCPAEPLAREGTLWEALRALLPHSKEDLKLDLGEKVERSVVTLLQ RATELFYEGRRDECLQSSEVILDYSWEKLNTGTWQDVDKDWRRVYAIGCL LKALCLCQAPEDANTVAAALRVCDMGLLMGAAILGDILLKVAAILQTHLP GKRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFL VPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQ TLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDG EEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALY PHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWH YVRALDLSFSVSFWWS
Sequence Similarities:	Contains 1 JmjC domain.
Expression System:	Wheat germ
Protein Length:	Full length protein; 1 to 416
Warning:	This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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