SETD7 Protein, Human, Recombinant (His Tag)

Inquiry
  • Specification
  • Related Products
Cat.No.:  PE-2023
Product Overview:  Human SETD7 (NP_085151.1) (Asp 2-Lys 366) with a polyhistidine tag at the N-terminus.
Background:  Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of thehistone-lysine methyltransferase family and SET7 subfamily. SETD7 is widely expressed and expressed in pancreatic islets. SETD7 contains three MORN repeats and one SET domain. SETD7 plays a central role in the transcriptional activation of genes such as collagenase or insulin. As a protein lysine methyltransferase (PKMT), SETD7 also has methyltransferase activity toward non-histone proteins such as p53/TP53, TAF1, and possibly TAF7 by recognizing and binding in substrate proteins. The mono-methyltransferase activity of SETD7 is achieved by disrupting the formation at near-attack conformations for the dimethylation reaction. SETD7 is also a novel coactivator of NF-kappaB and plays a role in inflammation and diabetes.
Applications:  ELISA; Western Blot , Enzyme activity assay
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Molecular Weight:  The recombinant human SETD7 comprises 372 amino acids and has a predicted molecular mass of 41.5 kDa. It migrates as an approximately 48 kDa band in SDS-PAGE under reducing conditions.
Purity:  > 94 % as determined by SDS-PAGE
Species:  Human
Formulation:  Lyophilized from sterile PBS, pH 7.41.
Accession#:  NP_085151.1
Alternative Names:  KMT7 Protein, Human; SET7 Protein, Human; SET7/9 Protein, Human; SET9 Protein, Human
Tag:  His
Expression System:  E. coli
Common Name:  SET domain containing (lysine methyltransferase) 7
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Online Inquiry

For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Products

USA

Quick Links

Easy access to products and services you need from our library via powerful searching tools

Privacy Policy | Cookie Policy

Copyright © 2026 CD BioSciences. All Rights Reserved.