At least three systems including DNA methylation, histone modification and non-coding RNA (ncRNA)-associated gene silencing are currently thought to initiate and sustain epigenetic changes. The types of proteins and enzymes involved in these processes is numerous.

CD BioSciences offers recombinant proteins and native proteins from a variety of sources to meet your epigenetic research needs. Our proteins and enzymes include, but are not limited to, DNA methylation proteins, RNA methylation proteins, chromatin remodeling factors, histones, and various histone modifying enzymes (i.e. writer enzymes, eraser enzymes), as well as reader domain-containing proteins. These high-quality proteins and enzymes can be used in antibody production, structural analysis, and biochemical assays related to epigenetic research (such as Western blotting or enzymatic activity analysis).

As an international leading supplier of epigenetic protein products, CD BioSciences not only provides a wide range of off-the-shelf epigenetic proteins and enzymes, but also can custom-produce according to your specific requirements. Moreover, for industrial customers, our protein expression and purification platform can meet the requirements of bulk protein production, GMP protein production, protein modification and engineering.

Advantages of Our Proteins & Enzymes:

Wide Coverage

1. More than 5,000 proteins/enzymes/protein complexes involved in epigenetic regulation in stock;
2. Native, synthetic and recombinant proteins, and recombinant proteins are produced from multiple expression systems (E. coli, yeast, baculovirus-insect, mammalian cells and plant expression systems…);
3. Multiple species (human, monkey, bovine, cow, chicken, mouse, rat, rabbit, zebrafish…);
4. Recombinant proteins with different tags (His, GST, Strep, Flag, Fc, HA, T7, MBP, Avi, SOMO…) on N-terminus or C-terminus;
5. Full-length or partial fragments with various mutations.

Cost-effective Quality Products

1. Most of the products with > 90% purity as determined by SDS-PAGE and/or HPLC;
2. Most of the products with < 0.1 EU/μg endotoxin level as determined by LAL assay;
3. Validated bio-activity using functional ELISA and/or other activity assays;
4. CD BioSciences saves your money with competitive prices and a custom one-stop solution.