Small molecules targeting proteins or enzymes involved in the epigenetic modification are useful for investigating the physiological consequences caused by epigenetic modification. As epigenetic dysregulation is associated with many diseases, these bioactive small molecules represent important tools for researchers to conduct drug discovery programs.
CD BioSciences has numerous small-molecule epigenetic modulators (activators, antagonists and inhibitors) that target changes to DNA modification and histone modification (i.e. writer enzymes, eraser enzymes, and reader domain-containing proteins). In addition, we can also provide bioactive small molecules related to the DNA damage repair pathway and protein ubiquitination system.
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